rs2506116706

This variant is located in the PKMYT1 gene.

ClinVar annotation

Uncertain Significance☆☆☆
1 submitter

not specified

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About PKMYT1

This gene encodes a member of the serine/threonine protein kinase family. The encoded protein is a membrane-associated kinase that negatively regulates the G2/M transition of the cell cycle by phosphorylating and inactivating cyclin-dependent kinase 1. The activity of the encoded protein is regulated by polo-like kinase 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]

View all PKMYT1 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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