rs2509715
This is a regulatory region variant variant in the ACY3 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
N-acetylkynurenine (2) measurement
Surendran P et al. “Rare and common genetic determinants of metabolic individuality and their effects on human health.” Nature Medicine 28(11):2321-2332 (2022)
Allele A
OR 0.26
p 5.0e-51
N 14,296
Large GWAS
European
About ACY3
Predicted to enable aminoacylase activity. Located in extracellular exosome. [provided by Alliance of Genome Resources, Jul 2025]
View all ACY3 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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