rs2516049

This is a intergenic variant variant.

GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

Epstein Barr virus nuclear antigen 1 IgG measurement

Zhou Y et al. Genetic loci for Epstein-Barr virus nuclear antigen-1 are associated with risk of multiple sclerosis. Multiple Sclerosis (houndmills, Basingstoke, England) 22(13):1655-1664 (2016)
Allele T
OR 0.20
p 3.0e-20
N 6,547
Large GWAS
Hispanic or Latin American

blood immunoglobulin amount

Tengvall K et al. Molecular mimicry between Anoctamin 2 and Epstein-Barr virus nuclear antigen 1 associates with multiple sclerosis risk. Proceedings of the National Academy of Sciences of the United States of America 116(34):16955-16960 (2019)
Allele G
OR 0.09
p 7.0e-15
N 11,936
Large GWAS
European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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