rs2517521
This is a coding sequence variant variant in the HCG22 gene.
▶GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
health trait
Schoeler T et al. “Combining cross-sectional and longitudinal genomic approaches to identify determinants of cognitive and physical decline.” Nature Communications 16(1):4524 (2025)
Allele A
OR 0.02
p 1.0e-40
N 405,979
Large GWAS
European
disease
Schoeler T et al. “Participation bias in the UK Biobank distorts genetic associations and downstream analyses.” Nature Human Behaviour 7(7):1216-1227 (2023)
Allele A
OR 0.04
p 5.0e-9
N 283,743
Major Consortium StudyLarge GWAS
European
grip strength measurement
Schoeler T et al. “Combining cross-sectional and longitudinal genomic approaches to identify determinants of cognitive and physical decline.” Nature Communications 16(1):4524 (2025)
Allele A
OR 0.01
p 4.0e-8
N 404,112
Large GWAS
European
About HCG22
Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Jul 2025]
View all HCG22 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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