rs2524649054

This variant is located in the PIK3R3 gene.

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ClinVar annotation

Uncertain Significance★☆☆☆

1 submitter

not specified

About PIK3R3

Phosphatidylinositol 3-kinase (PI3K) phosphorylates phosphatidylinositol and similar compounds, which then serve as second messengers in growth signaling pathways. PI3K is composed of a catalytic and a regulatory subunit. The protein encoded by this gene represents a regulatory subunit of PI3K. The encoded protein contains two SH2 domains through which it binds activated protein tyrosine kinases to regulate their activity. [provided by RefSeq, Jun 2016]

View all PIK3R3 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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