rs2532402
This is a upstream gene variant variant in the KANSL1 gene.
▶GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
taste liking measurement
May-Wilson S et al. “Large-scale GWAS of food liking reveals genetic determinants and genetic correlations with distinct neurophysiological traits.” Nature Communications 13(1):2743 (2022)
Allele G
OR 0.03
p 1.0e-14
N 152,847
Large GWAS
European
physical activity measurement
Qi G et al. “Genome-wide association studies of 27 accelerometry-derived physical activity measurements identified novel loci and genetic mechanisms.” Genetic Epidemiology 46(2):122-138 (2022)
Allele G
OR —
β 0.040
p 2.0e-12
N 88,411
Large GWAS
European
neuroimaging measurement
Bhatt RR et al. “The Genetic Architecture of the Human Corpus Callosum and its Subregions.” Nature Communications 16(1):9708 (2025)
Allele C
OR 1.71
p 3.0e-11
N 46,685
Large GWAS
European
About KANSL1
This gene encodes a nuclear protein that is a subunit of two protein complexes involved with histone acetylation, the MLL1 complex and the NSL1 complex. The encoded protein has been implicated in a variety of cellular processes including enhancer regulation, cell proliferation, and mitosis. Mutations in this gene are associated with Koolen-de Vries Syndrome. [provided by RefSeq, May 2022]
View all KANSL1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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