rs2535633
This is a downstream gene variant variant in the ITIH4 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
body mass index
Wen W et al. “Meta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass index.” Human Molecular Genetics 23(20):5492-504 (2014)
Allele G
OR 0.03
p 2.0e-10
N 86,739
Meta-analysisLarge GWAS
multi-ancestry
About ITIH4
The protein encoded by this gene is secreted into the blood, where it is cleaved by plasma kallikrein into two smaller forms. Expression of this gene has been detected only in liver, and it seems to be upregulated during surgical trauma. This gene is part of a cluster of similar genes on chromosome 3. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
View all ITIH4 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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