rs2547231

This variant is located in the SULT2A1 gene.

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GWAS Catalog Trait Associations (4)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

X-11440-to-4-androsten-3beta,17beta-diol disulfate 2 ratio

Shin SY et al. “An atlas of genetic influences on human blood metabolites.” Nature Genetics 46(6):543-550 (2014)
Allele A
OR 0.14
p 3.0e-191
N 5,485
Large GWAS
European

5alpha-androstan-3beta,17beta-diol disulfate measurement

Shin SY et al. “An atlas of genetic influences on human blood metabolites.” Nature Genetics 46(6):543-550 (2014)
Allele A
OR 0.08
p 3.0e-22
N 7,345
Large GWAS
European

X-12850 measurement

Shin SY et al. “An atlas of genetic influences on human blood metabolites.” Nature Genetics 46(6):543-550 (2014)
Allele A
OR 0.06
p 4.0e-16
N 6,251
Large GWAS
European

X-12456 measurement

Shin SY et al. “An atlas of genetic influences on human blood metabolites.” Nature Genetics 46(6):543-550 (2014)
Allele A
OR 0.04
p 3.0e-11
N 4,774
Large GWAS
European

About SULT2A1

This gene encodes a member of the sulfotransferase family. Sulfotransferases aid in the metabolism of drugs and endogenous compounds by converting these substances into more hydrophilic water-soluble sulfate conjugates that can be easily excreted. This protein catalyzes the sulfation of steroids and bile acids in the liver and adrenal glands, and may have a role in the inherited adrenal androgen excess in women with polycystic ovary syndrome. [provided by RefSeq, Mar 2010]

View all SULT2A1 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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