rs2562152
This is a upstream gene variant variant in the RHBDF1 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
central nervous system cancer, glioblastoma multiforme
Melin BS et al. “Genome-wide association study of glioma subtypes identifies specific differences in genetic susceptibility to glioblastoma and non-glioblastoma tumors.” Nature Genetics 49(5):789-794 (2017)
Allele T
OR 1.21
p 2.0e-8
N 24,381
Large GWAS
European
About RHBDF1
Predicted to enable growth factor binding activity and serine-type endopeptidase activity. Involved in several processes, including negative regulation of protein secretion; regulation of epidermal growth factor receptor signaling pathway; and regulation of proteasomal protein catabolic process. Located in Golgi membrane and endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Jul 2025]
View all RHBDF1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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