rs2578475

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GWAS Catalog Trait Associations (6)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

amygdala volume

Ji Y et al. “Cross-ancestry and sex-stratified genome-wide association analyses of amygdala and subnucleus volumes.” Nature Genetics 57(4):839-850 (2025)
Allele G
OR 0.08
p 3.0e-41
N 42,397
Large GWAS
multi-ancestry
Mufford MS et al. “The Genetic Architecture of Amygdala Nuclei.” Biological Psychiatry 95(1):72-84 (2024)
Allele G
OR 25.60
p 7.0e-27
N 36,352
Large GWAS
multi-ancestry

dentate gyrus volume

Liu N et al. “Cross-ancestry genome-wide association meta-analyses of hippocampal and subfield volumes.” Nature Genetics 55(7):1126-1137 (2023)
Allele G
OR 0.05
p 3.0e-11
N 38,977
Large GWAS
European, East Asian

hippocampal CA4 volume

Liu N et al. “Cross-ancestry genome-wide association meta-analyses of hippocampal and subfield volumes.” Nature Genetics 55(7):1126-1137 (2023)
Allele G
OR 0.05
p 2.0e-10
N 38,977
Large GWAS
European, East Asian

hippocampal CA3 volume

Liu N et al. “Cross-ancestry genome-wide association meta-analyses of hippocampal and subfield volumes.” Nature Genetics 55(7):1126-1137 (2023)
Allele G
OR 0.04
p 4.0e-9
N 38,977
Large GWAS
European, East Asian

hippocampal CA1 volume

Liu N et al. “Cross-ancestry genome-wide association meta-analyses of hippocampal and subfield volumes.” Nature Genetics 55(7):1126-1137 (2023)
Allele G
OR 0.04
p 2.0e-8
N 38,977
Large GWAS
European, East Asian

hippocampal volume

Liu N et al. “Cross-ancestry genome-wide association meta-analyses of hippocampal and subfield volumes.” Nature Genetics 55(7):1126-1137 (2023)
Allele G
OR 0.04
p 1.0e-8
N 38,977
Large GWAS
European, East Asian

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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