rs2620636

This is a downstream gene variant variant in the ARHGAP39 gene.

GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

aspartate aminotransferase to alanine aminotransferase ratio

Sinnott-Armstrong N et al. Genetics of 35 blood and urine biomarkers in the UK Biobank. Nature Genetics 53(2):185-194 (2021)
Allele T
OR 0.04
p 8.0e-13
N 354,455
Major Consortium StudyLarge GWAS
multi-ancestry

About ARHGAP39

Predicted to enable GTPase activator activity. Involved in postsynapse organization. Is active in glutamatergic synapse. [provided by Alliance of Genome Resources, Jul 2025]

View all ARHGAP39 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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