rs2634458

This is a intron variant variant in the PSD3 gene.

▶

GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

breast cancer

Hsu YC et al. “The largest genome-wide association study for breast cancer in Taiwanese Han population.” Breast Cancer Research and Treatment 203(2):291-306 (2024)

Allele T

OR 1.27

p 9.0e-13

N 12,480

Large GWAS

East Asian

About PSD3

Predicted to enable guanyl-nucleotide exchange factor activity and phospholipid binding activity. Predicted to be involved in regulation of ARF protein signal transduction. Predicted to be located in membrane. Predicted to be active in glutamatergic synapse; postsynapse; and ruffle membrane. [provided by Alliance of Genome Resources, Apr 2025]

View all PSD3 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

Community Wiki

No community notes yet for this variant. Sign in to start one.

Comments

Loading comments…