rs2644109

This is a downstream gene variant variant in the IPO9 gene.

GWAS Catalog Trait Associations (4)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

body mass index

Harris BHL et al. New role of fat-free mass in cancer risk linked with genetic predisposition. Scientific Reports 14(1):7270 (2024)
Allele T
OR 0.03
p 4.0e-23
N 342,566
Large GWAS
European

fat pad mass

Harris BHL et al. New role of fat-free mass in cancer risk linked with genetic predisposition. Scientific Reports 14(1):7270 (2024)
Allele T
OR 0.02
p 2.0e-18
N 337,196
Large GWAS
European

lean body mass

Harris BHL et al. New role of fat-free mass in cancer risk linked with genetic predisposition. Scientific Reports 14(1):7270 (2024)
Allele T
OR 0.01
p 5.0e-16
N 337,739
Large GWAS
European

About IPO9

Enables histone binding activity; histone chaperone activity; and nuclear import signal receptor activity. Involved in proteasome localization and protein import into nucleus. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025]

View all IPO9 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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