rs2659009
This variant is located in the NDUFAF8 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
IgG fucosylation measurement
Shen X et al. “Multivariate discovery and replication of five novel loci associated with Immunoglobulin G N-glycosylation.” Nature Communications 8(1):447 (2017)
Allele A
OR —
p 4.0e-11
N 1,960
Large GWAS
European
▶ClinVar annotation
Benign★★★☆
3 submitters1 publicationnot provided; Gastric cancer; Uterine carcinosarcoma; Lung cancer; Malignant lymphoma, large B-cell, diffuse; Ovarian serous cystadenocarcinoma
View on ClinVar →About NDUFAF8
Involved in mitochondrial respiratory chain complex I assembly. Located in mitochondrial matrix. Implicated in nuclear type mitochondrial complex I deficiency 34. [provided by Alliance of Genome Resources, Jul 2025]
View all NDUFAF8 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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