rs266717

This variant is located in the LINC02043 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

adiponectin measurement

Richards JB et al. “A genome-wide association study reveals variants in ARL15 that influence adiponectin levels.” Plos Genetics 5(12):e1000768 (2009)
Allele C
OR 1.07
p 9.0e-19
N 8,531
Large GWAS
European
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Research that mentions this SNP (1)

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Relationship between ADIPOQ gene, circulating high molecular weight adiponectin and albuminuria in individuals with normal kidney function: evidence from a family-based study
AssociationN=634Menzaghi C. et al.(2011)· Diabetologia

Family-based study of 634 non-diabetic individuals examining the ADIPOQ gene and albuminuria. rs17300539 in the ADIPOQ promoter was significantly associated with albumin-creatinine ratio (ACR, p=0.0027) and explained 4% of variance, and with HMW adiponectin levels (β=0.26, p=4.8×10⁻⁵). Variance component analysis showed ACR heritability of h²=0.20 and positive genetic correlation with HMW adiponectin (ρg=0.38, p=0.04), suggesting ADIPOQ variants modulate albuminuria levels.

Traits studied:Albuminuria (albumin-creatinine ratio)HMW adiponectin levels
PubMedDOIMetascience Observatory

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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