rs2696497
This is a regulatory region variant variant in the LRRC37A gene.
▶GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
alcohol consumption quality
Saunders GRB et al. “Genetic diversity fuels gene discovery for tobacco and alcohol use.” Nature 612(7941):720-724 (2022)
Allele T
OR 0.02
p 3.0e-25
N 2,965,643
Large GWAS
European, East Asian, Hispanic or Latin American, African unspecified
feeling "fed-up" measurement
Nagel M et al. “Item-level analyses reveal genetic heterogeneity in neuroticism.” Nature Communications 9(1):905 (2018)
Allele T
OR 7.92
p 2.0e-15
N 374,971
Large GWAS
European
brain age measurement
Oppenheimer H et al. “No causal links between estradiol and female's brain and mental health using Mendelian randomization.” Nature Communications 16(1):10915 (2025)
Allele T
OR 0.32
p 3.0e-10
N 14,287
Large GWAS
European
About LRRC37A
Predicted to be located in membrane. [provided by Alliance of Genome Resources, Jul 2025]
View all LRRC37A variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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