rs2733289
This is a intron variant variant in the PDZRN4 gene.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
body mass index
Sakaue S et al. “A cross-population atlas of genetic associations for 220 human phenotypes.” Nature Genetics 53(10):1415-1424 (2021)
Allele C
OR 0.01
p 2.0e-11
N 523,818
Large GWAS
multi-ancestry
type 2 diabetes mellitus
Vujkovic M et al. “Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ancestry meta-analysis.” Nature Genetics 52(7):680-691 (2020)
Allele C
OR 0.03
p 4.0e-11
N 1,114,458
Meta-analysisLarge GWAS
European
About PDZRN4
Predicted to enable zinc ion binding activity. [provided by Alliance of Genome Resources, Jul 2025]
View all PDZRN4 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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