rs2760980

This is a intergenic variant variant.

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GWAS Catalog Trait Associations (4)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

blood protein amount

Orrù V et al. “Complex genetic signatures in immune cells underlie autoimmunity and inform therapy.” Nature Genetics 52(10):1036-1045 (2020)

Allele A

OR 1.05

p 2.0e-60

N 1,635

Large GWAS

European

rheumatoid arthritis, drug use measurement

Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)

Allele G

OR 0.26

p 5.0e-57

N 404,034

Major Consortium StudyLarge GWAS

multi-ancestry

macrophage colony-stimulating factor 1 receptor level

Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)

Allele A

OR 0.06

p 1.0e-16

N 47,745

Large GWAS

European

Parkinson disease

Doostparast Torshizi A et al. “Proteogenomic network analysis reveals dysregulated mechanisms and potential mediators in Parkinson's disease.” Nature Communications 15(1):6430 (2024)

Allele A

OR 0.15

p 3.0e-9

N 539,017

Large GWAS

European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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