rs27619
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
proto-oncogene tyrosine-protein kinase receptor Ret measurement
▶Research that mentions this SNP (1)
▶Association of ERAP1, but not IL23R, with ankylosing spondylitis in a Han Chinese populationAssociationN=1,472Stuart I. Davidson et al.(2009)· Arthritis & Rheumatism
This case-control study examined polymorphisms in ERAP1 and IL23R genes in a Han Chinese population with ankylosing spondylitis (527 cases, 945 controls). Multiple SNPs in ERAP1 were significantly associated with AS (rs27980 P=0.0048, rs7711564 P=0.0081), confirming the gene's role across different ethnic populations. However, no association was found between IL23R and AS, with the key nonsynonymous SNP rs11209026 not polymorphic in Chinese individuals, suggesting different disease pathogenesis mechanisms between Chinese and Caucasian populations.
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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