rs2820465

▶

GWAS Catalog Trait Associations (3)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

Umbilical hernia

Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)

Allele G

OR 0.14

p 2.0e-35

N 622,865

Major Consortium StudyLarge GWAS

multi-ancestry

Wei J et al. “Identification of fifty-seven novel loci for abdominal wall hernia development and their biological and clinical implications: results from the UK Biobank.” Hernia : the Journal of Hernias and Abdominal Wall Surgery 26(1):335-348 (2022)

Allele G

OR 1.20

p 8.0e-17

N 275,546

Major Consortium StudyLarge GWAS

European

posterior thigh muscle fat infiltration measurement

van der Meer D et al. “The link between liver fat and cardiometabolic diseases is highlighted by genome-wide association study of MRI-derived measures of body composition.” Communications Biology 5(1):1271 (2022)

Allele G

OR 8.67

p 5.0e-18

N 32,956

Large GWAS

European

anterior thigh muscle fat infiltration measurement

van der Meer D et al. “The link between liver fat and cardiometabolic diseases is highlighted by genome-wide association study of MRI-derived measures of body composition.” Communications Biology 5(1):1271 (2022)

Allele G

OR 6.99

p 3.0e-12

N 32,911

Large GWAS

European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

Community Wiki

No community notes yet for this variant. Sign in to start one.

Comments

Sign in to join the discussion.

Loading comments…