rs28368148
This is a protein-altering variant in the IFNA10 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
COVID-19
Pairo-Castineira E et al. “GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19.” Nature 617(7962):764-768 (2023)
Allele G
OR 0.75
p 4.0e-8
N 2,974,917
Meta-analysisLarge GWAS
multi-ancestry
Kousathanas A et al. “Whole-genome sequencing reveals host factors underlying critical COVID-19.” Nature 607(7917):97-103 (2022)
Allele G
OR —
p 2.0e-8
N 55,891
Large GWAS
multi-ancestry
About IFNA10
This gene encodes a protein that belongs to the type I interferon family of proteins, and is located in a cluster of alpha interferon genes on chromosome 9. Interferons are small regulatory molecules that function in cell signaling in response to viruses and other pathogens or tumor cells. This gene is intronless and the encoded protein is secreted. [provided by RefSeq, Aug 2013]
View all IFNA10 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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