rs2837148
This variant is located in the IGSF5 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
breast cancer
Hsu YC et al. “The largest genome-wide association study for breast cancer in Taiwanese Han population.” Breast Cancer Research and Treatment 203(2):291-306 (2024)
Allele A
OR 0.51
p 6.0e-12
N 12,480
Large GWAS
East Asian
About IGSF5
Predicted to enable PDZ domain binding activity. Predicted to be involved in cell-cell adhesion. Predicted to be located in apical plasma membrane. Predicted to be active in bicellular tight junction and cell surface. [provided by Alliance of Genome Resources, Apr 2025]
View all IGSF5 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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