rs28428925

This is a intron variant variant in the BBX gene.

GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

multisite chronic pain

Johnston KJA et al. Genome-wide association study of multisite chronic pain in UK Biobank. Plos Genetics 15(6):e1008164 (2019)
Allele G
OR 0.02
p 1.0e-9
N 387,649
Major Consortium StudyLarge GWAS
European

About BBX

Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within bone development. Predicted to be located in chromatin. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Jul 2025]

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Gene information from NCBI Gene. Variant classifications from ClinVar.

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