rs284662
This variant is located in the B3GNT8 gene.
▶GWAS Catalog Trait Associations (7)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (7)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
n-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2 measurement
Pietzner M et al. “Mapping the proteo-genomic convergence of human diseases.” Science (new York, N.y.) 374(6569):eabj1541 (2021)
Allele T
OR 0.49
p —
N 10,708
Large GWAS
European
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8 measurement
Pietzner M et al. “Mapping the proteo-genomic convergence of human diseases.” Science (new York, N.y.) 374(6569):eabj1541 (2021)
Allele T
OR 0.68
p —
N 10,708
Large GWAS
European
blood protein amount
Gudjonsson A et al. “A genome-wide association study of serum proteins reveals shared loci with common diseases.” Nature Communications 13(1):480 (2022)
Allele T
OR 0.33
p 6.0e-73
N 5,359
Large GWAS
European
body height
Yengo L et al. “A saturated map of common genetic variants associated with human height.” Nature 610(7933):704-712 (2022)
Allele T
OR 0.03
p 2.0e-51
N 455,180
Large GWAS
Hispanic or Latin American
level of disintegrin and metalloproteinase domain-containing protein 23 in blood serum
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele C
OR 0.05
p 5.0e-30
N 47,745
Large GWAS
European
phosphopantothenoylcysteine decarboxylase measurement
Kuliesius J et al. “Efficient candidate drug target discovery through proteogenomics in a Scottish cohort.” Communications Biology 8(1):1300 (2025)
Allele C
OR 0.96
p 7.0e-26
N 195
Small GWAS
European
level of ephrin type-A receptor 4 in blood serum
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele C
OR 0.04
p 6.0e-14
N 47,745
Large GWAS
European
▶ClinVar annotation
Benign★★★☆
2 submitters1 publicationAbout B3GNT8
Enables protein N-acetylglucosaminyltransferase activity. Involved in poly-N-acetyllactosamine biosynthetic process. Located in extracellular exosome. [provided by Alliance of Genome Resources, Jul 2025]
View all B3GNT8 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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