rs28478453
This is a intron variant variant in the GATAD2A gene.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
Headache, glucose measurement
Islam MR et al. “Cross-trait analyses identify shared genetics between migraine, headache, and glycemic traits, and a causal relationship with fasting proinsulin.” Human Genetics 142(8):1149-1172 (2023)
Allele G
OR 1.02
p 9.0e-10
N 786,347
Large GWAS
European
atrial fibrillation
Yuan S et al. “Cross-population GWAS and proteomics improve risk prediction and reveal mechanisms in atrial fibrillation.” Nature Communications 16(1):6426 (2025)
Allele C
OR 0.03
p 3.0e-8
N 1,840,341
Large GWAS
European
About GATAD2A
Enables protein-macromolecule adaptor activity. Involved in chromatin remodeling and negative regulation of DNA-templated transcription. Located in nucleoplasm. Part of NuRD complex. [provided by Alliance of Genome Resources, Jul 2025]
View all GATAD2A variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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