rs2853880

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GWAS Catalog Trait Associations (4)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

HLA class II histocompatibility antigen, DM alpha chain measurement

Sun BB et al. “Genomic atlas of the human plasma proteome.” Nature 558(7708):73-79 (2018)

Allele G

OR —

β 0.310

p 2.0e-29

N 3,301

Large GWAS

European

low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio

Karjalainen MK et al. “Genome-wide characterization of circulating metabolic biomarkers.” Nature 628(8006):130-138 (2024)

Allele C

OR 0.06

p 4.0e-28

N 136,016

Large GWAS

multi-ancestry

low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio

Karjalainen MK et al. “Genome-wide characterization of circulating metabolic biomarkers.” Nature 628(8006):130-138 (2024)

Allele C

OR 0.06

p 8.0e-25

N 136,016

Large GWAS

multi-ancestry

esterified cholesterol measurement, low density lipoprotein cholesterol measurement

Karjalainen MK et al. “Genome-wide characterization of circulating metabolic biomarkers.” Nature 628(8006):130-138 (2024)

Allele C

OR 0.04

p 5.0e-11

N 136,016

Large GWAS

multi-ancestry

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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