rs28661185
This variant is located in the NT5DC2 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
cortical thickness
van der Meer D et al. “The genetic architecture of human cortical folding.” Science Advances 7(51):eabj9446 (2021)
Allele T
OR 9.47
p 3.0e-21
N 33,748
Large GWAS
European
About NT5DC2
Predicted to enable 5'-nucleotidase activity. Predicted to be involved in negative regulation of dopamine biosynthetic process; negative regulation of oxidoreductase activity; and negative regulation of peptidyl-serine phosphorylation. Located in mitochondrion. [provided by Alliance of Genome Resources, Jul 2025]
View all NT5DC2 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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