rs2897442
This variant is located in the KIF3A gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
atopic eczema
Paternoster L et al. “Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis.” Nature Genetics 47(12):1449-1456 (2015)
Allele C
OR 1.09
p 1.0e-10
N 116,863
Large GWAS
multi-ancestry
Paternoster L et al. “Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis.” Nature Genetics 44(2):187-92 (2011)
Allele C
OR 1.11
p 4.0e-8
N 26,171
Meta-analysisLarge GWAS
European
About KIF3A
Enables protein phosphatase binding activity; small GTPase binding activity; and spectrin binding activity. Involved in protein localization to cell junction and protein transport. Located in centriole; centrosome; and spindle microtubule. Part of kinesin II complex. Biomarker of silicosis. [provided by Alliance of Genome Resources, Jul 2025]
View all KIF3A variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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