rs2942003
This variant is located in the LRRC37A2 gene.
▶GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
t-tau measurement
Sarnowski C et al. “Meta-analysis of genome-wide association studies identifies ancestry-specific associations underlying circulating total tau levels.” Communications Biology 5(1):336 (2022)
Allele T
OR 0.16
p 2.0e-78
N 14,721
Meta-analysisLarge GWAS
European
health trait
Schoeler T et al. “Combining cross-sectional and longitudinal genomic approaches to identify determinants of cognitive and physical decline.” Nature Communications 16(1):4524 (2025)
Allele T
OR 0.01
p 6.0e-25
N 405,979
Large GWAS
European
total cortical area measurement
Smith SM et al. “An expanded set of genome-wide association studies of brain imaging phenotypes in UK Biobank.” Nature Neuroscience 24(5):737-745 (2021)
Allele G
OR 0.10
p 5.0e-17
N 21,282
Major Consortium StudyLarge GWAS
European
About LRRC37A2
Predicted to enable ATP binding activity; ATP hydrolysis activity; and metal ion binding activity. Predicted to be involved in SNARE complex disassembly and protein transport. Predicted to be located in cytoplasm and membrane. [provided by Alliance of Genome Resources, Jul 2025]
View all LRRC37A2 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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