rs294381
This is a upstream gene variant variant in the MPPED2 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
risk-taking behaviour
Karlsson Linnér R et al. “Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.” Nature Genetics 51(2):245-257 (2019)
Allele T
OR 0.02
p 1.0e-14
N 404,291
Large GWAS
European
About MPPED2
Predicted to enable manganese ion binding activity; phosphoric diester hydrolase activity; and purine ribonucleotide binding activity. [provided by Alliance of Genome Resources, Jul 2025]
View all MPPED2 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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