rs294775
This is a upstream gene variant variant in the UGT2B10 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
cotinine measurement
Buchwald J et al. “Genome-wide association meta-analysis of nicotine metabolism and cigarette consumption measures in smokers of European descent.” Molecular Psychiatry 26(6):2212-2223 (2021)
Allele C
OR 0.35
p 2.0e-21
N 5,185
Meta-analysis
European
About UGT2B10
Predicted to enable UDP-glycosyltransferase activity. Predicted to be involved in estrogen metabolic process. Predicted to be located in endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Jul 2025]
View all UGT2B10 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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