rs2954026

GWAS Catalog Trait Associations (5)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

coronary artery disease

Allele T
OR 1.05
p 5.0e-10
N 392,241
Meta-analysisLarge GWAS
multi-ancestry

phospholipids:total lipids ratio, blood VLDL cholesterol amount

Karjalainen MK et al. Genome-wide characterization of circulating metabolic biomarkers. Nature 628(8006):130-138 (2024)
Allele T
OR 0.03
p 7.0e-10
N 136,016
Large GWAS
multi-ancestry

triglyceride measurement, high density lipoprotein cholesterol measurement

Allele G
OR 0.16
p 8.0e-9
N 22,161
Major Consortium StudyLarge GWAS
European

cholesteryl esters to total lipids in small HDL percentage

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele G
OR 0.05
p 6.0e-61
N 241,027
Large GWAS
European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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