rs2964911

This variant is located in the LINC03000 gene.

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Research that mentions this SNP (1)

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A Bivariate Mann‐Whitney Approach for Unraveling Genetic Variants and Interactions Contributing to Comorbidity
AssociationN=5,376Yalu Wen et al.(2013)· Genetic Epidemiology

A bivariate Mann-Whitney (BMW) approach was developed to identify genetic variants and interactions contributing to nicotine dependence (ND) and alcohol dependence (AD) comorbidity. Analysis of 184 known AD and ND SNPs in the SAGE dataset identified rs16969968 in CHRNA5 associated with both AD and ND in Caucasian samples (P = 8.23 × 10⁻³ in COGA, P = 1.06 × 10⁻³ in FSCD). The GG genotype showed increased risk for both conditions, with odds ratios of 0.678 (95% CI: 0.501-0.919) for comorbidity in COGA.

Traits studied:Alcohol dependenceComorbidity of nicotine and alcohol dependenceNicotine dependence
PubMedDOIMetascience Observatory

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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