rs3017895
This is a coding sequence variant variant in the FAM13A gene.
▶Research that mentions this SNP (1)
▶High expression of FAM13A was associated with increasing the liver cirrhosis riskAssociationN=644Yingai Zhang et al.(2019)· Molecular Genetics & Genomic Medicine
This case-control study examined FAM13A gene polymorphisms in 260 liver cirrhosis patients and 384 controls. The minor allele 'A' of rs3017895 was associated with increased liver cirrhosis risk (OR = 1.32, 95% CI = 1.03-1.68, p = 0.028). The G-A haplotype of rs3017895-rs1059122 significantly increased cirrhosis risk (OR = 1.34, 95% CI = 1.04-1.73, p = 0.026). Immunohistochemistry showed FAM13A expression was significantly higher in cirrhotic liver tissue compared to normal tissue.
About FAM13A
Predicted to enable GTPase activator activity. Predicted to be involved in regulation of small GTPase mediated signal transduction. Predicted to be located in cytosol. Implicated in chronic obstructive pulmonary disease. [provided by Alliance of Genome Resources, Jul 2025]
View all FAM13A variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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