rs3109109

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GWAS Catalog Trait Associations (3)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

monocyte measurement

Akbari P et al. “A genome-wide association study of blood cell morphology identifies cellular proteins implicated in disease aetiology.” Nature Communications 14(1):5023 (2023)

Allele C

OR 0.13

p 6.0e-29

N 39,586

Large GWAS

European

gut microbiome measurement

Qin Y et al. “Combined effects of host genetics and diet on human gut microbiota and incident disease in a single population cohort.” Nature Genetics 54(2):134-142 (2022)

Allele C

OR 0.05

p 5.0e-8

N 5,959

Large GWAS

European

monocyte count

Chen MH et al. “Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations.” Cell 182(5):1198-1213.e14 (2020)

Allele C

OR —

p 6.0e-11

N 639,696

Large GWAS

multi-ancestry

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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