rs3130561

This is a downstream gene variant variant in the PSORS1C1 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

saturated fatty acids to total fatty acids percentage

Sun Y et al. “GWAS and multi-omics integrative analysis reveal novel loci and their molecular mechanisms for circulating fatty acids.” Hgg Advances 6(4):100470 (2025)

Allele T

OR —

p 2.0e-12

N 239,268

Large GWAS

European

Yuan F et al. “Blood metabolic biomarkers and colorectal cancer risk: results from large prospective cohort and Mendelian randomisation analyses.” British Journal of Cancer 133(1):94-103 (2025)

Allele T

OR 0.02

p 6.0e-12

N 199,732

Large GWAS

European

About PSORS1C1

This gene is one of several genes thought to confer susceptibility to psoriasis and systemic sclerosis, located on chromosome 6 near the major histocompatibility complex (MHC) class I region. [provided by RefSeq, Sep 2011]

View all PSORS1C1 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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