rs3135002
This is a regulatory region variant variant.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
C-peptide measurement
▶Research that mentions this SNP (1)
▶Meta-genome-wide association studies identify a locus on chromosome 1 and multiple variants in the MHC region for serum C-peptide in type 1 diabetesMeta-analysisN=3,479Delnaz Roshandel et al.(2018)· Diabetologia
Meta-genome-wide association study of 3,479 European participants with type 1 diabetes identified a locus on chromosome 1 (rs559047, p=4.13×10⁻⁸) and multiple variants in the MHC region (rs61211515, rs9260151, rs3135002) associated with C-peptide levels as a measure of beta cell function. These associations partly differ from known type 1 diabetes risk loci, suggesting distinct mechanisms for disease development versus progression.
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
Community Wiki
No community notes yet for this variant. Sign in to start one.
Comments
Sign in to join the discussion.
Loading comments…