rs332827

This variant is located in the NFIA gene.

▶

GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

social inhibition quality, attention deficit hyperactivity disorder, substance abuse

Karlsson Linnér R et al. “Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction.” Nature Neuroscience 24(10):1367-1376 (2021)

Allele G

OR 0.01

p 3.0e-17

N 2,776,348

Large GWAS

European

risk-taking behaviour

Karlsson Linnér R et al. “Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.” Nature Genetics 51(2):245-257 (2019)

Allele A

OR 0.01

p 5.0e-14

N 975,353

Large GWAS

European

▶

ClinVar annotation

Benign★★★☆

2 submitters1 publication

View on ClinVar →

About NFIA

This gene encodes a member of the NF1 (nuclear factor 1) family of transcription factors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

View all NFIA variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

Community Wiki

No community notes yet for this variant. Sign in to start one.

Comments

Loading comments…