rs334699
This is a intron variant variant in the NFIA gene.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
nodular goiter
White SL et al. “Global multi-ancestry genome-wide analyses identify genes and biological pathways associated with thyroid cancer and benign thyroid diseases.” Nature Genetics 58(2):307-316 (2026)
Allele G
OR 0.23
p 8.0e-81
N 2,460,445
Large GWAS
multi-ancestry
hormone measurement, Thyroid stimulating hormone level
Porcu E et al. “A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function.” Plos Genetics 9(2):e1003266 (2013)
Allele A
OR 0.14
p 5.0e-12
N 26,420
Meta-analysisLarge GWAS
European
About NFIA
This gene encodes a member of the NF1 (nuclear factor 1) family of transcription factors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
View all NFIA variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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