rs34010330

This is a intron variant variant in the ELL gene.

GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

smoking initiation

Saunders GRB et al. Genetic diversity fuels gene discovery for tobacco and alcohol use. Nature 612(7941):720-724 (2022)
Allele C
OR 0.01
p 2.0e-16
N 2,669,029
Large GWAS
European

amygdala volume

Mufford MS et al. The Genetic Architecture of Amygdala Nuclei. Biological Psychiatry 95(1):72-84 (2024)
Allele C
OR 2.13
p 7.0e-10
N 36,352
Large GWAS
multi-ancestry

About ELL

Enables phosphatase binding activity. Involved in positive regulation of DNA-templated transcription and snRNA transcription. Located in cytosol; euchromatin; and nuclear body. Part of transcription elongation factor complex. [provided by Alliance of Genome Resources, Apr 2025]

View all ELL variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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