rs34245511
This is a intron variant variant in the LIMA1 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
colorectal cancer
Whiffin N et al. “Identification of susceptibility loci for colorectal cancer in a genome-wide meta-analysis.” Human Molecular Genetics 23(17):4729-37 (2014)
Allele C
OR 1.14
p 3.0e-8
N 13,443
Meta-analysisLarge GWAS
European
About LIMA1
This gene encodes a cytoskeleton-associated protein that inhibits actin filament depolymerization and cross-links filaments in bundles. It is downregulated in some cancer cell lines. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and expression of some of the variants maybe independently regulated. [provided by RefSeq, Aug 2011]
View all LIMA1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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