rs34459162
This is a protein-altering variant in the RCN3 gene.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
fructosamine measurement
Loomis SJ et al. “Genome-Wide Association Study of Serum Fructosamine and Glycated Albumin in Adults Without Diagnosed Diabetes: Results From the Atherosclerosis Risk in Communities Study.” Diabetes 67(8):1684-1696 (2018)
Allele C
OR 0.02
p 5.0e-9
N 9,751
CohortLarge GWAS
multi-ancestry
total glycated albumin
Loomis SJ et al. “Genome-Wide Association Study of Serum Fructosamine and Glycated Albumin in Adults Without Diagnosed Diabetes: Results From the Atherosclerosis Risk in Communities Study.” Diabetes 67(8):1684-1696 (2018)
Allele C
OR 0.03
p 4.0e-8
N 9,751
CohortLarge GWAS
multi-ancestry
About RCN3
Enables calcium ion binding activity. Involved in several processes, including collagen biosynthetic process; positive regulation of peptidase activity; and regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Jul 2025]
View all RCN3 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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