rs34601117
This variant is located in the TNFRSF10A gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
tumor necrosis factor receptor superfamily member 10A amount
▶ClinVar annotation
not provided; Colon adenocarcinoma; Colorectal cancer; Sarcoma; Lymphoma; Ovarian serous cystadenocarcinoma; Chronic lymphocytic leukemia/small lymphocytic lymphoma; Familial pancreatic carcinoma; Thymoma; Malignant tumor of esophagus; Cervical cancer; Clear cell carcinoma of kidney; Malignant lymphoma, large B-cell, diffuse; Acute myeloid leukemia; Lung cancer
View on ClinVar →About TNFRSF10A
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. [provided by RefSeq, Jul 2008]
View all TNFRSF10A variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
Community Wiki
No community notes yet for this variant. Sign in to start one.
Comments
Sign in to join the discussion.
Loading comments…