rs34697209

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GWAS Catalog Trait Associations (4)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

breast cancer, chronotype measurement

Wu X et al. “Using human genetics to understand the phenotypic association between chronotype and breast cancer.” Journal of Sleep Research 33(3):e13973 (2024)

Allele A

OR —

p 3.0e-13

N 696,907

Large GWAS

European

smoking initiation

Saunders GRB et al. “Genetic diversity fuels gene discovery for tobacco and alcohol use.” Nature 612(7941):720-724 (2022)

Allele G

OR 0.00

p 6.0e-10

N 3,382,012

Large GWAS

European, East Asian, Hispanic or Latin American, African unspecified

chronotype measurement, estrogen-receptor positive breast cancer

Wu X et al. “Using human genetics to understand the phenotypic association between chronotype and breast cancer.” Journal of Sleep Research 33(3):e13973 (2024)

Allele A

OR —

p 2.0e-9

N 625,209

Large GWAS

European

estrogen-receptor negative breast cancer, chronotype measurement

Wu X et al. “Using human genetics to understand the phenotypic association between chronotype and breast cancer.” Journal of Sleep Research 33(3):e13973 (2024)

Allele A

OR —

p 9.0e-9

N 577,176

Large GWAS

European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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