rs34872892

This is a intron variant variant in the TMPRSS11E gene.

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GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

testosterone measurement

Venkatesh SS et al. “Genome-wide analyses identify 25 infertility loci and relationships with reproductive traits across the allele frequency spectrum.” Nature Genetics 57(5):1107-1118 (2025)

Allele G

OR 0.02

p 3.0e-10

N 246,862

Large GWAS

European, South Asian

erythrocyte volume

Astle WJ et al. “The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.” Cell 167(5):1415-1429.e19 (2016)

Allele G

OR 0.03

p 6.0e-9

N 172,433

Large GWAS

European

About TMPRSS11E

Predicted to enable serine-type peptidase activity. Involved in cognition. Predicted to be located in extracellular region and membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]

View all TMPRSS11E variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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