rs35317317

This variant is located in the ZNF652-AS1 gene.

GWAS Catalog Trait Associations (13)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

cholesterol to total lipids in medium VLDL percentage

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele A
OR 0.02
p 9.0e-22
N 450,015
Large GWAS
multi-ancestry

triglycerides to total lipids in medium VLDL percentage

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele A
OR 0.02
p 5.0e-20
N 450,015
Large GWAS
multi-ancestry

triglycerides to total lipids in very large VLDL percentage

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele A
OR 0.02
p 3.0e-16
N 450,015
Large GWAS
multi-ancestry

free cholesterol to total lipids in medium VLDL percentage

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele A
OR 0.02
p 4.0e-16
N 450,015
Large GWAS
multi-ancestry

cholesterol to total lipids in small VLDL percentage

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele A
OR 0.02
p 2.0e-14
N 450,015
Large GWAS
multi-ancestry

total lipids in medium VLDL

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele A
OR 0.01
p 7.0e-13
N 450,015
Large GWAS
multi-ancestry

phospholipids in very large HDL measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele A
OR 0.01
p 2.0e-12
N 450,015
Large GWAS
multi-ancestry

total lipids in very large HDL measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele A
OR 0.01
p 3.0e-12
N 450,015
Large GWAS
multi-ancestry

Diuretic use measurement

Allele A
OR 0.06
p 2.0e-11
N 229,086
Major Consortium StudyLarge GWAS
European

total lipids in large HDL

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele A
OR 0.01
p 2.0e-11
N 450,015
Large GWAS
multi-ancestry

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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