rs35457250
This variant is located in the AHSG gene.
▶GWAS Catalog Trait Associations (21)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (21)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
ectonucleoside triphosphate diphosphohydrolase 5 measurement
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.65
p 6.0e-118
N 47,745
Large GWAS
European
level of phospholipase A2 inhibitor and Ly6/PLAUR domain-containing protein in blood
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.45
p 3.0e-90
N 47,745
Large GWAS
European
level of von Willebrand factor A domain-containing protein 1 in blood
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.48
p 2.0e-58
N 47,745
Large GWAS
European
GDH/6PGL endoplasmic bifunctional protein measurement
Allele T
OR 1.99
p 1.0e-56
N 3,301
Large GWAS
European
level of tectonic-3 in blood
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.37
p 3.0e-56
N 47,745
Large GWAS
European
beta-galactoside alpha-2,6-sialyltransferase 1 measurement
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.45
p 3.0e-51
N 47,745
Large GWAS
European
dipeptidyl peptidase 2 measurement
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.35
p 2.0e-41
N 47,745
Large GWAS
European
level of nucleotide exchange factor SIL1 in blood
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.42
p 1.0e-35
N 47,745
Large GWAS
European
sPARC-related modular calcium-binding protein 1 measurement
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.27
p 7.0e-24
N 47,745
Large GWAS
European
asialoglycoprotein receptor 2 measurement
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.28
p 9.0e-23
N 47,745
Large GWAS
European
▶ClinVar annotation
Benign★★★☆
3 submitters2 publicationsAbout AHSG
The protein encoded by this gene is a negatively-charged serum glycoprotein that is synthesized by hepatocytes. The encoded protein consists of two polypeptide chains, which are both cleaved from a proprotein encoded from a single mRNA. It is involved in several processes, including endocytosis, brain development, and the formation of bone tissue. Defects in this gene are a cause of susceptibility to leanness. [provided by RefSeq, Aug 2017]
View all AHSG variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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