rs35597084

This is a intron variant variant in the NFKBIL1 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

Sepsis, mortality

Butler-Laporte G et al. “Elevated body mass index is associated with an increased risk of infectious disease admissions and mortality: a mendelian randomization study.” Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases (2020)

Allele C

OR 0.17

p 4.0e-8

N 2,037

Large GWAS

European

About NFKBIL1

This gene encodes a divergent member of the I-kappa-B family of proteins. Its function has not been determined. The gene lies within the major histocompatibility complex (MHC) class I region on chromosome 6. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2009]

View all NFKBIL1 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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