rs356182

This is a intron variant variant in the LOC124900602 gene.

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GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

Parkinson disease

Kim JJ et al. “Multi-ancestry genome-wide association meta-analysis of Parkinson's disease.” Nature Genetics 56(1):27-36 (2024)
Allele A
OR —
p 4.0e-170
N 2,525,730
Meta-analysisLarge GWAS
multi-ancestry
Nalls MA et al. “Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies.” The Lancet. Neurology 18(12):1091-1102 (2019)
Allele A
OR 0.28
p 4.0e-154
N 482,730
Meta-analysisLarge GWAS
European
Chang D et al. “A meta-analysis of genome-wide association studies identifies 17 new Parkinson's disease risk loci.” Nature Genetics 49(10):1511-1516 (2017)
Allele A
OR 1.33
p 5.0e-123
N 417,508
Meta-analysisLarge GWAS
European
Nalls MA et al. “Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease.” Nature Genetics 46(9):989-93 (2014)
Allele A
OR 1.32
p 4.0e-73
N 108,990
Meta-analysisLarge GWAS
European
Bandres-Ciga S et al. “The Genetic Architecture of Parkinson Disease in Spain: Characterizing Population-Specific Risk, Differential Haplotype Structures, and Providing Etiologic Insight.” Movement Disorders : Official Journal of the Movement Disorder Society 34(12):1851-1863 (2019)
Allele A
OR 0.22
p 2.0e-9
N 7,588
Large GWAS
European
Pan H et al. “Genome-wide association study using whole-genome sequencing identifies risk loci for Parkinson's disease in Chinese population.” Npj Parkinson's Disease 9(1):22 (2023)
Allele A
OR 0.34
p 3.0e-53
N 4,450
Large GWAS
East Asian

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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