rs35749011
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
Parkinson disease
Nalls MA et al. “Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies.” The Lancet. Neurology 18(12):1091-1102 (2019)
Allele A
OR 0.61
p 2.0e-70
N 482,730
Meta-analysisLarge GWAS
European
Chang D et al. “A meta-analysis of genome-wide association studies identifies 17 new Parkinson's disease risk loci.” Nature Genetics 49(10):1511-1516 (2017)
Allele A
OR 1.72
p 3.0e-35
N 417,508
Meta-analysisLarge GWAS
European
Nalls MA et al. “Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease.” Nature Genetics 46(9):989-93 (2014)
Allele A
OR 1.82
p 1.0e-29
N 108,990
Meta-analysisLarge GWAS
European
Rodrigo LM et al. “Imputation and Reanalysis of ExomeChip Data Identifies Novel, Conditional and Joint Genetic Effects on Parkinson's Disease Risk.” Genes 12(5) (2021)
Allele A
OR 2.24
p 5.0e-11
N 10,533
Large GWAS
European
Lewy body dementia
Guerreiro R et al. “Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study.” The Lancet. Neurology 17(1):64-74 (2018)
Allele G
OR 2.27
p 7.0e-10
N 5,007
Large GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
Community Wiki
No community notes yet for this variant. Sign in to start one.
Comments
Sign in to join the discussion.
Loading comments…